Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women
Hypothyroidism is a clinical and biochemical syndrome. The objectives of this study were to describe and establish the most prevalent clinical and biochemical characteristics at the time of the diagnosis of hypothyroidism in adult women. To do so, a descriptive, retrospective and cross-sectional stu...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | Spanish |
| Published: |
Facultad de Ciencias Exactas, Químicas y Naturales
2019
|
| Subjects: | |
| Online Access: | https://www.fceqyn.unam.edu.ar/recyt/index.php/recyt/article/view/230 |
| _version_ | 1824325788468510720 |
|---|---|
| author | Villalba Rinck Hansen, Mariana D. Haseitel, Mariel Martinez, Mariano Bonneau, Graciela A. |
| author_facet | Villalba Rinck Hansen, Mariana D. Haseitel, Mariel Martinez, Mariano Bonneau, Graciela A. |
| author_sort | Villalba Rinck Hansen, Mariana D. |
| collection | Revista de Ciencia y Tecnologia RECyT |
| description | Hypothyroidism is a clinical and biochemical syndrome. The objectives of this study were to describe and establish the most prevalent clinical and biochemical characteristics at the time of the diagnosis of hypothyroidism in adult women. To do so, a descriptive, retrospective and cross-sectional study was carried out. Two hundred and three clinical histories of women diagnosed with hypothyroidism from the Hospital Escuela de Agudos Dr. Ramón Madariaga, Posadas (Misiones) were selected. The most prevalent clinical feature was asthenia and it was present in 41% (n = 83) of the patients. 46% presented hypertriglyceridemia, 39% hypercholesterolemia, 38% altered fasting glycaemia, 17% hypertension, 23% overweight and 52% obesity. Women with clinical hypothyroidism showed a 5 times higher risk of presenting high levels of triglycerides than women with subclinical hypothyroidism (OR = 5.2; 95% CI = 1.93-14.04). All women presented at least one clinical or biochemical characteristic, being the most frequent, within the latter, hypertriglyceridemia and altered fasting glycaemia. |
| format | Online |
| id | ojs-article-230 |
| institution | Facultad de Ciencias Exactas Quimicas y Naturales |
| language | Spanish |
| publishDate | 2019 |
| publisher | Facultad de Ciencias Exactas, Químicas y Naturales |
| record_format | ojs |
| spelling | ojs-article-2302020-03-09T12:43:34Z Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women Características clínicas y bioquímicas al momento del diagnóstico de hipotiroidismo en mujeres adultas Villalba Rinck Hansen, Mariana D. Haseitel, Mariel Martinez, Mariano Bonneau, Graciela A. Subclinical hypothyroidism Clinical hypothyroidism asthenia hypertriglyceridemia dysglycemia Hipotiroidismo subclínico Hipotiroidismo clínico astenia hipertrigliceridemia disglucemia Hypothyroidism is a clinical and biochemical syndrome. The objectives of this study were to describe and establish the most prevalent clinical and biochemical characteristics at the time of the diagnosis of hypothyroidism in adult women. To do so, a descriptive, retrospective and cross-sectional study was carried out. Two hundred and three clinical histories of women diagnosed with hypothyroidism from the Hospital Escuela de Agudos Dr. Ramón Madariaga, Posadas (Misiones) were selected. The most prevalent clinical feature was asthenia and it was present in 41% (n = 83) of the patients. 46% presented hypertriglyceridemia, 39% hypercholesterolemia, 38% altered fasting glycaemia, 17% hypertension, 23% overweight and 52% obesity. Women with clinical hypothyroidism showed a 5 times higher risk of presenting high levels of triglycerides than women with subclinical hypothyroidism (OR = 5.2; 95% CI = 1.93-14.04). All women presented at least one clinical or biochemical characteristic, being the most frequent, within the latter, hypertriglyceridemia and altered fasting glycaemia. El hipotiroidismo es un síndrome clínico y bioquímico. Los objetivos del presente trabajo fueron describir y establecer las características clínicas y bioquímicas más prevalentes al momento del diagnóstico de hipotiroidismo en mujeres adultas. Para ello se realizó un estudio descriptivo, retrospectivo y de corte transversal. Se seleccionaron 203 historias clínicas de mujeres con diagnóstico de hipotiroidismo del Hospital Escuela de Agudos Dr. Ramón Madariaga, Posadas (Misiones). La característica clínica más prevalente fue la astenia y se presentó en el 41% (n=83) de las pacientes. El 46% presentó hipertrigliceridemia, 39% hipercolesterolemia, 38% glucemia en ayunas alterada, 17% hipertensión, 23% sobrepeso y 52% obesidad. Las mujeres con hipotiroidismo clínico mostraron 5 veces más riesgo de presentar triglicéridos elevados que las mujeres con hipotiroidismo subclínico (OR=5,2; IC 95%= 1,93-14,04). Todas presentaron al menos una característica clínica o bioquímica, siendo las más frecuentes, dentro de estas últimas, la hipertrigliceridemia y la glucemia en ayunas alterada. Facultad de Ciencias Exactas, Químicas y Naturales 2019-05-28 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.fceqyn.unam.edu.ar/recyt/index.php/recyt/article/view/230 Argentine Journal of Science and Technology; Vol. 31 No. 1 (2019); 105-110 Revista de Ciencia y Tecnología; Vol. 31 Núm. 1 (2019); 105-110 1851-7587 0329-8922 spa https://www.fceqyn.unam.edu.ar/recyt/index.php/recyt/article/view/230/465 Derechos de autor 2019 Revista de Ciencia y Tecnología |
| spellingShingle | Subclinical hypothyroidism Clinical hypothyroidism asthenia hypertriglyceridemia dysglycemia Hipotiroidismo subclínico Hipotiroidismo clínico astenia hipertrigliceridemia disglucemia Villalba Rinck Hansen, Mariana D. Haseitel, Mariel Martinez, Mariano Bonneau, Graciela A. Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title | Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title_alt | Características clínicas y bioquímicas al momento del diagnóstico de hipotiroidismo en mujeres adultas |
| title_full | Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title_fullStr | Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title_full_unstemmed | Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title_short | Clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| title_sort | clinical and biochemical characteristics at the time of diagnosis of hypothyroidism in adult women |
| topic | Subclinical hypothyroidism Clinical hypothyroidism asthenia hypertriglyceridemia dysglycemia Hipotiroidismo subclínico Hipotiroidismo clínico astenia hipertrigliceridemia disglucemia |
| topic_facet | Subclinical hypothyroidism Clinical hypothyroidism asthenia hypertriglyceridemia dysglycemia Hipotiroidismo subclínico Hipotiroidismo clínico astenia hipertrigliceridemia disglucemia |
| url | https://www.fceqyn.unam.edu.ar/recyt/index.php/recyt/article/view/230 |
| work_keys_str_mv | AT villalbarinckhansenmarianad clinicalandbiochemicalcharacteristicsatthetimeofdiagnosisofhypothyroidisminadultwomen AT haseitelmariel clinicalandbiochemicalcharacteristicsatthetimeofdiagnosisofhypothyroidisminadultwomen AT martinezmariano clinicalandbiochemicalcharacteristicsatthetimeofdiagnosisofhypothyroidisminadultwomen AT bonneaugracielaa clinicalandbiochemicalcharacteristicsatthetimeofdiagnosisofhypothyroidisminadultwomen AT villalbarinckhansenmarianad caracteristicasclinicasybioquimicasalmomentodeldiagnosticodehipotiroidismoenmujeresadultas AT haseitelmariel caracteristicasclinicasybioquimicasalmomentodeldiagnosticodehipotiroidismoenmujeresadultas AT martinezmariano caracteristicasclinicasybioquimicasalmomentodeldiagnosticodehipotiroidismoenmujeresadultas AT bonneaugracielaa caracteristicasclinicasybioquimicasalmomentodeldiagnosticodehipotiroidismoenmujeresadultas |