| Summary: | In this study, we investigated the influence of subinhibitory concentrations of ciprofloxacin on enteropathogenic Escherichia coli (EPEC) virulence factors as motility, adherence, hemolysin
production and the interaction with some mechanisms of host defenses (phagocytosis). Adherence was investigated on bfp gene. The detection of bfp was reduced on 22% of the strains with 1/2 and 1/8 MIC, and on 11% of the strains with 1/4 and 1/16 MIC. We did not observe relevant differences on the hemolysin poduction, motility reduction or phagocytosis reduction on any of the studied strains. In view of these results, it could be important to continue with this kind of studies in order to
optimize simple therapeutic schemes for the treatment of uncomplicated infections, reducing the adverse reactions of some drugs on the host.
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